More Available Soon
Cannabinoid Quantification by uHPLC-Fourier Transform Mass Spectrometry
While the cheap and easy way to quantify cannabinoids is by liquid chromatography and UV absorbance, it is neither the most accurate nor sensitive. Furthermore, many compounds in food products may interfere with Cannabinoid absorbance. (Publication pending). We utilize Ultra High Pressure Liquid Chromatography (uHPLC) in tandem with Fourier Transform Mass Spectrometry. Sensitivity is extended by two orders of magnitude over UV technology and background compounds do not matter. Our routine analysis is based on this recent study Our libraries are based on exact mass modeling of the libraries from this comprehensive Time of Flight study.
By creating our own standard materials for minor cannabinoids we can extend our panels, with the goal of soon reaching absolute quantification of over 100 separate cannabinoids.
If you are having trouble getting reproducible measurements or want to see the whole cannabinoid profile for your complex product, Contact Us.
Targeted Protein Panels
Many places will offer you genetic sequencing of cannabis strains, however, these services are not direct measurements of your strain's characteristics. Unfortunately, RNA levels do not measure proteins and proteins are responsible for making your compounds of interest.
Furthermore, cannabinoid production is not mediated directly by mutational events. Cannabinoid production is mediated by post-translational modifications of proteins involved in their production. Mutations that affect the production of these valuable compounds do so by inactivating or hyper-activating the chemical modification sites. No amount of DNA or RNA sequencing can predict the potency or cannabinoid production of any strain. Investing in these technologies, while they may get you to the right question, is ultimately inefficient. Contact us for direct protein and PTM panels to truly characterize your new strain.
Identification of Microbes by Polymerase Chain Reaction
Plating for bacteria is error prone and costly. We are developing in house panels of primers based for the identification of microbes in cannabis products thanks to the recent release of the first fully annotated publicly available Cannabis genome. Kits available soon.